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Description
HNF6 is a member of the phylogenetically unrelated family of hepatocyte nuclear factors (HNFs) that regulate transcription of various genes, many of which are liver-specific. The HNF6 protein binds to promoters as a monomer, and contains a homeobox domain and a CUT DNA-binding domain. During embryonic development, HNF6 expression plays a key role in hepatic bilary tree development, and is used as a marker for hepatic lineage cells.
Source: Human
Tested Applications: SDS-PAGE, WB, ELISA, Dot
Sequence: Full length
Epitope tag(s): none
Size: 20 µg
Description: Recombinant full-length human HNF6 protein.
Expression:
Recombinant protein was expressed in E. coli and refolded to soluble form.
Formulation:
201 µg/ml (determined by Bradford assay) in 500 mM L-arginine, 300 mM guanidine-HCl, 50 mM HEPES, 5 mM cystamine, 5 mM cysteamine, 5 mM CaCl2,
3 mM DTT, pH 7.5
Preservative: none
Purity: >90% by SDS-PAGE
Storage: Store at -80 °C.
Avoid multiple freeze-thaws.
Alternative Names: Hepatocyte nuclear factor 6, alpha; HNF6 alpha; One cut homeobox 1; OC-1
Size: 465 residues; 51.0 kDa
Database Links:
RefSeq Protein NP_004489.1
RefSeq Gene NM_004498.1
UniProt Q9UBCO
Warranty
Each Lot has been verified to meet quality specifications in accordance with testing guidelines. We will replace the product if it does not conform to specifications. Product guaranteed for 6 months from date of purchase if stored as directed. This product must not be resold without written permission from Primorigen Biosciences.