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HumanKine™ GM-CSF

HumanKine™ GM-CSF
Prod. No.

Recombinant human GM-CSF, expressed in engineered human cells. GM-CSF belongs to the IL-2 protein family. GM-CSF is a 15 to 36 kDa monomeric glycoprotein. GM-CSF is produced by a number of different cell types, including activated T-cells, B-cells, mast cells, and endothelial cells. GM-CSF is required to develop neutrophilic colonies in vitro and GM-CSF synergizes with EPO in the proliferation of erythroid and megakaryocytic progenitor cells. GM-CSF promotes myeloid differentiation and generates granulocytes (basophils, neutrophils, and eosinophils) and macrophage colonies. GM-CSF triggers irreversible dfferentiation of myeloblasts and monoblasts and also increases the phagocytic capability of macrophages.

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