HumanKine™ IL-28B

Recombinant human IL-28B expressed in engineered human cells. IL-28B (IFN lambda 3) is a 24 kDa monomer and belongs to the type III interferon protein family. IL-28B has immunomodulatory activity and displays potent antiviral activity. The cytokine up-regulates MHC class I antigen expression and is the ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex may signal through the Jak-STAT pathway.