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Nkx2.2 Monoclonal Antibody PR-3B2

Nkx2.2 Monoclonal Antibody PR-3B2
Prod. No.


Nkx2.2 is a transcription factor belonging to NK-2 homeobox family. It is expressed in the ventral regions of the developing vertebrate central nervous system (CNS) and is therefore thought to play a role in the morphogenesis of the CNS. In addition, gene knockout experiments in mice have identified Nkx2.2 as a key regulator of insulin-producing beta-cell development in the pancreas. Nkx2.2 is used as a marker for pancreatic islet cell lineages when inducing differentiation of human stem cells.

Reacts with: Human*
Tested Applications: WB, ELISA
Host: Mouse
Clone: PR-3B2
Isotype: IgG2a, κ
Size: 100 µg

Recombinant human Nkx2.2 fragment (AA 1-127) expressed in E. coli and refolded to soluble form.

Purification: Protein G chromatography

Formulation: 1 mg/ml in PBS
Preservative: 0.09% NaN3

Storage: Store at 4ºC (<3 months) or -20ºC.
Avoid multiple freeze-thaws.

Recommended Uses:
Western Blot 1:1000-1:5000
ELISA (detect) 1:1000
Note: Optimal concentrations should be empirically determined.

Target Alternative Names:
Homeobox protein Nkx-2.2; Homeobox protein NK-2 homolog B; NK2 homeobox 2

Target Size: 273 AA; 30.1 kDa

Target Database Links:
RefSeq Protein NP_002500.1
RefSeq mRNA NM_002509.2
UniProt O95096


Each Lot has been verified to meet quality specifications in accordance with testing guidelines. We will replace the product if it does not conform to specifications. Product guaranteed for 6 months from date of purchase if stored as directed. This product must not be resold without written permission from Primorigen Biosciences.



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