SOX2 Recombinant Protein

Description:

SOX2 is a member of the large family of sex determining region Y-related HMG-box (SOX) transcription factors. SOX2 is expressed in embryonic stem cell lines, and decreased levels of SOX2 interfere with self renewal and pluripotency. SOX2 has been identified as one of the key regulators for induced pluripotent stem (iPS) cells. The DNA binding domain (AA 41-109) shows significant homology to other SOX family members, while the N-terminal (AA 1-38) and C-terminal (AA 194-317) regions are unique.

Source: Human
Tested Applications: SDS-PAGE, WB, ELISA, Dot
Sequence: Full length
Epitope tag(s): none

Size: 20 µg

Description: Recombinant full-length human SOX2 protein

Expression:
Recombinant protein was expressed in E. coli and refolded to soluble form.

Formulation:
209 µg/ml (determined by Bradford assay) in 500 mM L-arginine, 300 mM guanidine-HCl, 50 mM HEPES, 5 mM cystamine, 5 mM cysteamine, 5 mM CaCl2,
3 mM DTT, pH 7.5
Preservative: none

Purity: >90% by SDS-PAGE

Storage: Store at -80 °C.
Avoid multiple freeze-thaws.

Alternative Names:
Sex-determining region Y-box 2, SRY-box 2, ANOP3, MCOPS3, MGC2413

Size: 317 residues; 34.3 kDa

Database Links:
RefSeq Protein NP_003097.1
RefSeq Gene NM_003106.2
UniProt P48431

Warranty:

Each Lot has been verified to meet quality specifications in accordance with testing guidelines. We will replace the product if it does not conform to specifications. Product guaranteed for 6 months from date of purchase if stored as directed. This product must not be resold without written permission from Primorigen Biosciences.

S2100-20UG

S2100